MS D365 Vendor collaboration provide the functionality to create invoice against single purchase order from vendor collaboration module but there is a business case in which vendor can submit single invoice against multiple PO's, currently this scenario is possible in out of the box Accounts payables module. Future enhancement is required to add this provision/functionality on vendor collaboration module as well.
Under Review
Ideas Administrator

Appreciate you taking the time to submit the product suggestion. We will monitor the votes and other feedback to consider in future backlog.
Lachlan Cash – Principal Program Manager - Microsoft