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In general it is possible to deactivate the Autosave Functionality for a form. Here is the documented Code for it and it works:
https://docs.microsoft.com/en-us/dynamics365/customerengagement/on-premises/customize/manage-auto-save

The same code does not work when I want to deactivate the the Autosave Functionality for specific Editable Grids. After creating a Microsoft Ticket for this issue, I was told that this is "by design".

Why is this feature important?
When you are using Editable Grids, it get saved after every change. You have of course a different behaviour on the form directly. And there is the source of different problems, because processes gets triggered when not all data is available because the Editable Grid saves after every change. And that makes it really difficult to use Editable Grids and Forms atthe same time for an entity and have a complex business logic behind it.
Category: General
STATUS DETAILS
Needs Votes
Ideas Administrator

Thank you for your feedback.

Currently this is not in our roadmap; however, we are tracking it and if we get more feedback and votes, we may consider it in the future.

Sincerely,

PM, Microsoft.