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When the data is refreshed to a sandbox environment, retail retargeting job fails if the customer is using RSSU. For the re targeting job to go through, one should remove all Retail channel data groups and keep only the default channel data group. The job will succeeded only when all distribution jobs are applied in the retail DB.

The current Retail Redeployment package was released before RSSU was introduced and I assume it doesn't support an environment with RSSU.
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Ideas Administrator

By re-running the CSU (Self-hosted) installer to update any parameters, then running 9999 from Headquarters, the CSU should function again.  Unfortunately, due to it being a fully self-managed CSU, there is little that can be automated from the cloud.